USP 381: Elastomeric Closures
• Absorbance
• Acidity or Alkalinity
• Ammonium
• Extraction
– Drug Vehicle
– IPA
– Purified Water
• Determination of Color
• Extractable Zinc
• Fragmentation
• Heavy Metals
• Identity Test
• Opalescence
• Penetrability
• pH Change
• Reducing Substances
• Self-Sealing Capacity
• Total Extractables
• Turbidity
• Volatile Sulfides
